Healthy Life - My Good Received Verbalise At Christ University, Bangalore (6.8.15)
India: Pharmacy of the world
On 6.8.15 I had the practiced fortune to give a speak to B Sc students of Christ University, Bangalore. Christ University, Bangalore, is i of the best inward India, dedicated Fathers, faculty in addition to staff are aiming to construct this university, India’s best in addition to world-class. Kudos to the sagacious management of Christ University for making a world-class academy alongside a lively campus, mind-bogglingly splendid infrastructure in addition to a highly motivating atmosphere for learners in addition to teachers.
Here are some interesting snaps of my participation (giving the 45 infinitesimal lecture alongside a powerpoint to strengthen the message).
During the talk, I elaborated on the next points:
Bright prospects inward Indian Pharmaceutical Industry
‘It is a proud in addition to successful manufacture inward Republic of Republic of India today, exporting medicines to 220 countries inward the world. Over 60% of vaccines are produced inward India. There was zip prior to Independence. In the side past times side x years the pharma sector is expected to grow v times from introduce Rs. 2.00 lakh crore level’.
- physician Subburaj, Secretary, Pharmaceuticals – Ministry of Chemicals in addition to Fertilisers (IDMA Bulletin, 22 to xxx March 2015, page no. 36
We are talking of an industry, which has approximately, Rs. 1.00 lakh crores sales per annum inward domestic marketplace in addition to exports Rs. 1.00 lakh crores worth of products, making the full to approx. Rs. 2.00 lakh crores/annum.
By 2020, the full worth of line of piece of employment concern that the Indian pharmaceutical manufacture is expected to make is Rs. 10.00 lakh crores, this futurity increase indicates the fantabulous line of piece of employment concern in addition to chore prospects, for aspirants in addition to people inward the industry.
• Friends, nosotros are talking of an manufacture which provides anti-AIDS drugs at 1 dollar a day… Cipla has saved 1 crore lives inward Africa through their affordable anti -AIDS medicines: Republic of Republic of India makes 92% of anti-AIDS medications sold world-wide
• Today, according to estimates past times the World Health Organisation (WHO), every 3rd kid inward the globe — who is vaccinated through its programme — is protected through a vaccine manufactured inward India. No pocket-sized achievement for a province where the manufacture forever seeks to import technology
• Every 5th tablet, capsule in addition to injectable generic drug existence used inward the Blue Planet is manufactured inward India, according to India’s past times Health Minister Ghulam Nabi Azad
• Médecins Sans Frontières (MSF), the Blue Planet torso that helps needy countries, dubs Republic of Republic of India the ‘global chemist's shop of the world’
With the inward a higher house sparkling opener points, I was able to attract the wholesome attending of attendees in addition to hence I went onto elaborate points equally mentioned below (with several anecdotes in addition to comments):
The vibrant pharmaceutical manufacture inward Republic of Republic of India tin live on divided into 3 principal components: APIs (bulk drugs), finished formulations (branded in addition to unbranded) including vaccines in addition to biosimilars. (The term Biopharma includes biosimilars in addition to other products such equally vaccines, sera etc).
This numbers of inward a higher house components:
- As per AIOCD AWACS June 2015 MAT value: the Indian Pharmaceutical Industry is Rs. 90085 crores (July 2014 to June 2015), increase of 14.3%
- India exported $15.2 billion or Rs 94,275 crore of pharmaceutical products inward 2014-15, alongside EU accounting for a 5th or $3 billion, equally per Appaji of Pharmaexcil
- The Pharmaceutical manufacture inward Republic of Republic of India is the world's third-largest inward terms of book in addition to stands 14th inward terms of value
- India is amid the overstep 6 global pharmaceutical producers inward the world
- The country’s pharmaceutical manufacture accounts for well-nigh 1.4 per cent of the global pharmaceutical manufacture inward value terms in addition to 10 per cent inward book terms
- India’s pharma sales are expected to hand US$ 27 billion past times 2016
What are Indian pharmaceutical companies doing?
• Focus is on me-too products
• Branded generics
• Me-too biopharma (including biosimilar) products (using rDNA technology) (Eg., MAB or Monoclonal Antibody business)
• Bulk drugs
• Herbal extracts in addition to herbal formulations (including Ayurvedic)
• Vaccines
• Importing in addition to marketing (contract marketing)
• CRAMS: Contract Research in addition to Manufacturing Services; NDDS (Novel Drug Delivery System) inquiry in addition to novel production inquiry to some extent
• Exports worldwide
• Veterinary products
• Food supplements/nutrition products/nutraceuticals
Top twenty pharma companies
• Indian pharmaceutical manufacture is estimated to grow at twenty per cent chemical compound annual increase charge per unit of measurement (CAGR) over the side past times side v years, equally per Republic of Republic of India Ratings, a Fitch Group company
• The Indian pharma marketplace size is expected to grow to US$ 85 billion past times 2020
• Presently at that topographic point are 10,500 manufacturing units in addition to over 3,000 pharma companies inward India, growing at an special rate
• India has well-nigh 1,400 WHO GMP approved manufacturing units
• India has been accredited alongside roughly 1,105 CEPs, to a greater extent than than 950 TGA approvals in addition to 584 sites approved past times the USFDA
• Globally to a greater extent than than xc per cent of formulations approvals for Anti-retroviral (ARVs), Anti-tubercular & Anti-malarial (WHO pre-qualified) convey been granted to India
• Manufacturing costs inward Republic of Republic of India are roughly 35-40 per cent of those inward the USA due to depression installation in addition to manufacturing costs
• India accounts for 36.9 per cent (3,411) of the 9,296 Drug Master Files (DMFs) filed alongside the USA, which is the highest exterior of the USA (as on Dec 31, 2013)
• Higher spending on R&D, owing to products patents convey made Republic of Republic of India a major destination for generic drug manufacturing
• Cipla has saved 1 crore lives inward Africa through their affordable anti -AIDS medicines: Republic of Republic of India makes 92% of anti-AIDS medications sold world-wide
• Lupin is the 5th largest generic pharma society inward USA prescription market; fastest growing inward Nippon in addition to due south Africa; global leader inward anti TB mass drugs in addition to formulations
• Today, according to the estimates past times the World Health Organisation (WHO), every 3rd kid inward the globe — who is vaccinated through its programme — is protected through a vaccine manufactured inward India. No pocket-sized achievement for a province where the manufacture forever seeks to import technology
• Every 5th tablet, capsule in addition to injectable generic drug existence used inward the Blue Planet is manufactured inward India, according to India’s Health Minister Ghulam Nabi Azad
• Médecins Sans Frontières (MSF), the Blue Planet torso that helps needy countries, dubs Republic of Republic of India the ‘global chemist's shop of the world’
• The global pharmaceuticals marketplace is worth US$300 billion a year, a figure expected to ascension to US$400 billion inside 3 years
• The 10 largest drugs companies command over one-third of this market, several alongside sales of to a greater extent than than US$10 billion a twelvemonth in addition to profits margins of well-nigh 30%
• The cost of AIDS handling — a whopping $10,000 a twelvemonth — dropped past times to a greater extent than than xxx times to precisely $300 per twelvemonth precisely because ‘affordable excellence’ was business office of the deoxyribonucleic acid of Indian researchers
• Cipla of Bombay says it has developed its ain methods for producing the 3 drugs — stavudine, lamivudine in addition to nevirapine — thereby avoiding the procedure patents owned past times the major manufacturers inward India
• The society says it volition provide a combination of the drugs to the French charity Médecins sans Frontières (Doctors without Borders) for $350 a twelvemonth per patient, on status that the scheme provides the handling costless to patients
• Approximately seventy per cent of the patients inward developing countries, have Indian medicines through NGOs similar The Clinton Foundation, Bill & Melinda Gates Foundation, Doctors Without Borders, the UNCTAD etc
• Biologics are drugs whose active ingredients are sourced from living organisms hence these products are based on proteins, genes, etc, dissimilar normal small-molecule drugs where the active ingredient is a chemical
• Biosimilar sales grew 20% annually to Rs 2,000 crore or roughly 2.5% of overall marketplace sales at the destination of Nov 2014. Sales margins on biosimilar drugs arrive at from 20% to 80%
• In Apr 2013, Cipla started selling a biosimilar of the rheumatoid arthritis drug Enbrel alongside a launch cost of $100. The cost of the drug from the innovator, Amgen, was $133.
• Biocon’s CANMab, a pectus cancer therapy that is a generic of Roche’s Herceptin, was launched inward Feb 2014 alongside a 25% discount to the innovator price
• Bulk Drug Industry is the backbone of the self-reliant Pharmaceutical manufacture inward India
• The working capital alphabetic quality investment inward the pharma manufacture is well-nigh Rs.35,000 crores
• Today 90% of the domestic mass drugs requirement is met past times the Indian industry, itself
• The Bulk Drug manufacture contributed well-nigh Rs. 48,000 Crores worth of exports, during the twelvemonth 2010-2011 which is growing past times over 15%-20% every twelvemonth
• Over 45% of the world's mass drug requirement is met past times India
• The Rs 11,086-crore Lupin Ltd, the largest producer of Lisinopril inward the world, used inward the handling of high blood pressure level in addition to sold to around xxx pharma companies, both inward Republic of Republic of India in addition to overseas
• It makes Lisinopril inward both mass drug in addition to finished drug shape equally good equally Lisinopril formulations. Last year, Lupin produced 105 tonnes per annum of Lisinopril API, in addition to this twelvemonth is ramping it upward to 120 tonnes
• Indian mass drug manufacture to grow to US$ 17 billion past times 2014
The Indian Bulk Drug manufacture is expected to grow at a CAGR of 21% to hand US$16.91 billion past times 2013-14 equally per this study
The Indian Bulk Drug manufacture is expected to grow at a CAGR of 21% to hand US$16.91 billion past times 2013-14 equally per this study
• Cygnus estimates the size of the Indian mass drug manufacture for 2009-10 at US$ 11.54 billion, out of which exports contribute well-nigh US$ 7.5 billion, constituting 65% of the industry
• The Indian Contract Manufacturing marketplace stood at US$986m inward 2009 in addition to is expected to grow at a CAGR of 41.7% to hand US$5.63 billion past times 2014.
• “About 1/3rd of global vaccines are manufactured inward Hyderabad
• Hyderabad is already an established mass drug hub of the province in addition to well-nigh forty per cent of country’s pharmaceutical products are manufactured inward Hyderabad”
• Biopharma is the largest sector contributing well-nigh 62 per cent of the full revenue, alongside revenue generation to the melody of over Rs 12,600 crore (US$ 2.03 billion)
• The bio-pharma sector comprises vaccines, therapeutics in addition to diagnostics
• India produces 40-70 per cent of the WHO demand for DPT & BCG in addition to xc per cent of measles vaccine
• A recent written report estimates that the vaccine production sector volition shoot to an estimated $871 1000000 past times 2016, a sizable outflow from the 2011 value of the sector, which sat at $350 million
• Of course, Republic of Republic of India volition involve to fence alongside some other growing vaccines powerhouse inward the coming years: China
• The province is domicile to 12 major vaccine manufacturing facilities in addition to exports to 150 countries
• Much of India's vaccines marketplace depends on exports; they made upward 65% of the marketplace concluding twelvemonth (2012 statistics)
• Serum Institute of Republic of Republic of India Ltd., India's No. 1 Biotech Company in addition to the World's Largest Vaccine Manufacturer (by volume, to a greater extent than than 1.3 billion doses) which includes Polio vaccine
• Serum Inst. is i of the largest suppliers of vaccines to over a 140 countries and it is estimated that about 65% of the children inward the Blue Planet have at to the lowest degree one vaccine manufactured past times Serum Institute of Republic of Republic of India Ltd
• It is estimated the electrical flow Indian vaccine marketplace is around $900 million, alongside a potential to demeanor on $4.6 billion past times 2017
• As per 'Pharma Vision 2020', the Government of Republic of Republic of India aims to construct Republic of Republic of India a global leader inward end-to-end drug manufacturing
• Manufacturing costs inward Republic of Republic of India are roughly 35-40 per cent of those inward the USA due to depression installation in addition to manufacturing costs
• Pharmaceutical exports from Republic of Republic of India convey grown at a CAGR of 21 per cent over the concluding decade
• Indian vaccines are exported to 150 countries
• The projected human resources requirement inward the Indian pharma sector is estimated to live on well-nigh 21,50,000 past times 2020
TAKE HOME MESSAGE
• Pharmaceutical manufacture is shortly approx. Rs. 2.00 lakh crores per annum in addition to volition hand Rs. 10 lakh crores past times 2020
• Good reach inward HRD, Accounts/Finance, Manufacturing (QA, QC, Production, R & D…), Regulatory in addition to Marketing
• Futuristic… reach for entrepreneurial function (eg., PCD business)
• Knowledge based profession
• Global
Thanks to physician Ganesh Gaekwadji, Prof. of Zoology, Christ University, Bangalore for organizing
above speaking opportunity, due thank yous to physician Anthony, Prof.... at Christ University, Bangalore
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