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National Toxicology Program: Peer & World Review Of Jail Cellular Telephone Outcry Radiations Study Reports

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National Toxicology Program (NTP) Finds Cell Phone Radiation Causes Cancer
Nov 19, 2018

Review of the NTP in addition to Ramazzini Institute Studies 
by the Swiss Expert Group on EMF in addition to Non-Ionizing Radiation (BERENIS)

Conclusions

The NTP in addition to Ramazzini studies are most comprehensive fauna studies with regard to cancer in addition to exposure to mobile telephone in addition to base of operations station signals that convey been conducted to date. The scientific character in addition to measure of laboratory techniques are high, particularly inwards the NTP study…”

“The results of these ii fauna studies are of keen scientific relevance in addition to importance for wellness policy because according to the International Agency for Research on Cancer (IARC), positive results from fauna studies with lifetime exposure are really of import with regard to the classification of cancer opportunity of an agent, together with information from epidemiological in addition to mechanistic studies. Based on the observed evidence regarding a correlation betwixt mobile telephone purpose in addition to gliomas equally good equally acoustic neuroma, the latter information led to the IARC classification of mobile telephone radiations equally ‘possibly carcinogenic’ (group 2B) inwards 2011…”

“Despite the methodological differences, both novel fauna studies showed relatively consistent results inwards schwannomas in addition to gliomas, equally good equally a dose-dependent tendency to an increment inwards the carcinogenicity of these tumors. The NTP study used high whole-body doses (SAR – specific absorption rates) equally compared to the regulatory limits for whole-body exposure recommended past times ICNIRP. For the full general public, this bound is 0.08 W/kg, with Switzerland additionally having introduced lower precautionary limits. The query arises of how transferable the NTP study results are to real-life exposure of the public, considering that mobile telephone purpose exposes alone parts of the torso to EMF levels comparable to the ones applied to the whole fauna past times the NTP study. First, it is mutual exercise inwards toxicology to study higher doses to evaluate possible hazards of an agent. Second, the NTP study establish an increment inwards carcinogenicity for GSM in addition to CDMA exposure conditions. Since the findings are similar for both types of exposure, they bespeak that the modulation of the signals does non seem to live relevant. Third, mobile telephone purpose tin effort local SAR values upwards to 2 W/kg, averaged over a cube of 21 mm side length inwards the closest proximity of the telephone (e.g. at the ear, cheeks, hand, bag locations, etc.). Thus, the results of the NTP study are to a greater extent than oft than non relevant for the exposure province of affairs when using a mobile telephone unopen to the body. In contrast, the Ramazzini study observed carcinogenicity at levels equally high equally the environmental exposure limits, with no statistically important number at lower doses. However, a dose-dependent tendency was establish for malignant see schwannomas, which is consistent with the findings of the NTP study. This may bespeak that the non-significant increment inwards example numbers at lower exposure levels represents a truthful number that has non reached statistical significance due to the given sample size.

In summary, BERENIS supports a precautionary approach for regulating RF EMF based on the findings in addition to their evaluation. H5N1 total opportunity assessment analysis taking into concern human relationship all available studies (animal studies in addition to epidemiological studies) is necessary to assess whether the electrical flow standards should live changed."

Complete review:  http://bit.ly/NTPBerenis


Oct 24, 2018

Peer-reviewed comments on NTP cellular telephone radiations study past times Hardell in addition to Carlberg

    Hardell L, Carlberg M. Comments on the USA National Toxicology Program technical reports on toxicology in addition to carcinogenesis study inwards rats exposed to whole-body radiofrequency radiations at 900 MHz in addition to inwards mice exposed to whole-body radiofrequency radiations at 1,900 MHz. International Journal of Oncology. Published October 24, 2018. https://doi.org/10.3892/ijo.2018.4606

    Abstract

    During the purpose of handheld mobile in addition to cordless phones, the encephalon is the master copy target of radiofrequency (RF) radiation. An increased opportunity of developing glioma in addition to acoustic neuroma has been establish inwards human epidemiological studies. Primarily based on these findings, the International Agency for Research on Cancer (IARC) at the World Health Organization (WHO) classified inwards May, 2011 RF radiations at the frequency arrive at of xxx kHz‑300 GHz equally a ‘possible’ human carcinogen, Group 2B. H5N1 carcinogenic potential for RF radiations inwards fauna studies was already published inwards 1982. This has been confirmed over the years, to a greater extent than late inwards the Ramazzini Institute rat study. An increased incidence of glioma inwards the encephalon in addition to malignant schwannoma inwards the see was establish inwards the USA National Toxicology Program (NTP) study on rats in addition to mice. The NTP in conclusion study is to live published; however, the extended reports are published on the network for evaluation in addition to are reviewed herein inwards to a greater extent than item inwards relation to human epidemiological studies. Thus, the master copy aim of this study was to compare before human epidemiological studies with NTP findings, including a curt review of fauna studies. We conclude that in that location is clear evidence that RF radiations is a human carcinogen, causing glioma in addition to vestibular schwannoma (acoustic neuroma). There is some evidence of an increased opportunity of developing thyroid cancer, in addition to clear evidence that RF radiations is a multi‑site carcinogen. Based on the Preamble to the IARC Monographs, RF radiations should live classified equally carcinogenic to humans, Group 1.




    Sep 24, 2018

    Peer-reviewed comments on NTP prison theater Galvanic cell telephone information for assessing human wellness risks
    by Ronald Melnick, Former NTP Director of Special Programs

    Melnick RL. Commentary on the utility of the National Toxicology Program study on prison theater Galvanic cell telephone radiofrequency radiations information for assessing human wellness risks despite unfounded criticisms aimed at minimizing the findings of adverse wellness effects. Environ Res. 2018 Sep 19;168:1-6. doi: 10.1016/j.envres.2018.09.010. 


    Abstract

    The National Toxicology Program (NTP) conducted two-year studies of prison theater Galvanic cell telephone radiations inwards rats in addition to mice exposed to CDMA- or GSM-modulated radiofrequency radiations (RFR) at exposure intensities inwards the encephalon of rats that were similar to or alone slightly higher than potential, localized human exposures from prison theater Galvanic cell phones held side past times side to the head. This study was designed to examination the (null) hypothesis that prison theater Galvanic cell telephone radiations at non-thermal exposure intensities could non effort adverse wellness effects, in addition to to render dose-response information for whatever detected toxic or carcinogenic effects. 

    Partial findings released from that study showed significantly increased incidences and/or trends for gliomas in addition to glial prison theater Galvanic cell hyperplasias inwards the encephalon in addition to schwannomas in addition to Schwann prison theater Galvanic cell hyperplasias inwards the see of exposed manful soul rats. These results, equally good equally the findings of significantly increased deoxyribonucleic acid harm (strand breaks) inwards the brains of exposed rats in addition to mice, reduced pup nativity weights when important dams were exposed to GSM- or CDMA-modulated RFR, in addition to the induction of cardiomyopathy of the correct ventricle inwards manful soul in addition to woman soul rats clearly demonstrate that the nada hypothesis has been disproved. 

     The NTP findings are most of import because the International Agency for Research on Cancer (IARC) classified RFR equally a "possible human carcinogen" based largely on increased risks of gliomas in addition to acoustic neuromas (which are Schwann prison theater Galvanic cell tumors on the acoustic nerve) with long term users of prison theater Galvanic cell phones. The concordance betwixt rats in addition to humans inwards prison theater Galvanic cell type affected past times RFR strengthens the animal-to-human association. 

    This commentary addresses several unfounded criticisms most the blueprint in addition to results of the NTP study that convey been promoted to minimize the utility of the experimental information on RFR for assessing human wellness risks. In contrast to those criticisms, an adept peer-review panel late concluded that the NTP studies were good designed, in addition to that the results demonstrated that both GSM- in addition to CDMA-modulated RFR were carcinogenic to the see (schwannomas) in addition to encephalon (gliomas) of manful soul rats.


    Note: Dr. Melnick was a senior toxicologist in addition to Director of Special Programs inwards the Environmental Toxicology Program at the National Institute of Environmental Health Sciences, National Institutes of Health. He led the blueprint of the prison theater Galvanic cell telephone radiations studies discussed inwards this commentary.


    Sep 6, 2018

    Official Summary of Peer Review Meeting most the NTP's Cell Phone 
    Radiofrequency Radiation Studies

    The official summary of the three-day peer review coming together to hash out the draft technical reports most the prison theater Galvanic cell telephone radiations studies conducted past times the National Toxicology Program is instantly available.

    National Toxicology Program (NTP). Peer Review of the Draft NTP Technical Reports on Cell Phone Radiofrequency Radiation. National Institute of Environmental Health Sciences. 2018. pp. 1-51. 





    May 3, 2018

    Videos of NTP Peer Review Meeting

    Videos with closed captions for the peer review coming together of the draft NTP technical reports on prison theater Galvanic cell telephone radiations are instantly available on the NTP website at http://bit.ly/NTPvideos.





    April 10, 2018

    Experts Find "Clear Evidence" of Cancer from Cell Phone Radiation inwards NTP Study

    March 28, 2018 (Last updated Apr 10)

    Eleven experts convened past times the National Toxicology Program (NTP) over a 3 twenty-four lx minutes menstruation time period to review the draft technical reports from the NTP's prison theater Galvanic cell telephone radiations studies concluded that in that location is "clear evidence" that exposure to prison theater Galvanic cell telephone radiations caused a rare cancer inwards the hearts of manful soul rats, in addition to "there is equivocal evidence" inwards the hearts of woman soul rats.

    The adept panel equally good reported "some evidence" that prison theater Galvanic cell telephone radiations exposure caused encephalon cancer inwards manful soul in addition to woman soul rats in addition to cancer of the adrenal glands inwards manful soul rats. 

    Additionally, "equivocal evidence" of cancer opportunity was reported inwards the pituitary, adrenal, in addition to prostate glands in addition to pancreas in addition to liver inwards manful soul rats in addition to adrenal glands inwards woman soul rats.

    The mice inwards the study, exposed to a dissimilar prison theater Galvanic cell telephone radiations frequency than the rats (1800 MHz vs. 900 MHz), displayed less evidence of cancer risk. Equivocal evidence of cancer opportunity from prison theater Galvanic cell telephone radiations was reported for lymphoma inwards manful soul in addition to woman soul mice. Equivocal evidence was equally good reported for skin, lung, in addition to liver cancer inwards manful soul mice.

    In seven instances, the adept grouping upgraded the evaluations of evidence published past times NTP staff inwards the draft technical reports. Thus, the NTP scientists seem to convey been overly conservative inwards their assessment of the hazards of long-term exposure to prison theater Galvanic cell telephone radiation. According to a one-time NTP scientist, "There was never a fourth dimension when thus many upgrades were recommended."

    The next tabular array based upon NTP's official summary of actions compares the evaluations of evidence of carcinogenicity prepared past times NTP staff with the adept committee's findings. The two-page document which equally good contains the committee's findings for nonneoplastic lesions tin live exist downloaded from 
    http://bit.ly/NTP180330

    The presentations in addition to oral world comments are available at the next link: http://bit.ly/2qmvtQg.

    Definitions
    Clear Evidence of Carcinogenic Activity is demonstrated past times studies that are interpreted equally showing a dose-related (i) increment of malignant neoplasms, (ii) increment of a combination of malignant in addition to benign neoplasms, or (iii) marked increment of benign neoplasms if in that location is an indication from this or other studies of the mightiness of such tumors to progress to malignancy.
    Some Evidence of Carcinogenic Activity is demonstrated past times studies that are interpreted equally showing a chemical-related increased incidence of neoplasms (malignant, benign, or combined) inwards which the pull of the reply is less than that required for clear evidence.
    Equivocal Evidence of Carcinogenic Activity is demonstrated past times studies that are interpreted equally showing a marginal increment of neoplasms that may live chemically related.
    No Evidence of Carcinogenic Activity is demonstrated past times studies that are interpreted equally showing no chemical-related increases inwards malignant or benign neoplasms.
    https://ntp.niehs.nih.gov/results/pubs/longterm/defs/index.html 
    Note: Although the definitions typically are applied to chemic agents, NTP equally good uses them with physical agents similar prison theater Galvanic cell telephone radiation.

    PDF of document equally good includes nonneoplastic results & definitions: http://bit.ly/NTP180330



    March 16, 2018 (Updated March 25)

    To thought webcast of NTP review coming together on March 26-28 from 8:30 AM - 5:00 PM EDT: 
    https://www.niehs.nih.gov/news/webcasts/cellphones_032618/

    The National Toxicology Program (NTP) requested public comments about the ii draft NTP Technical Reports on Cell Phone Radiofrequency Radiation. Due to a lag betwixt when comments were submitted in addition to posted to the NTP website, below are links to selected comments from scientists in addition to environmental wellness organizations most the reports.


    Public Comments: Scientists

    George Carlo, PhD, The Science in addition to Public Policy Institute

    C.K. Chou, PhD, CK Chou Consulting

    Lennart Hardell, MD, PhD, Michael Carlberg, MSc, University Hospital, Örebro, Sweden; Lena Hedendahl, MD, The Environment in addition to Cancer Research Foundation

    Magda Havas, PhD, Trent University 

    Ronald Kostoff, PhD

    Ronald Melnick, PhD, Retired Senior Toxicologist, National Toxicology Program

    Joel Moskowitz, PhD, University of California, Berkeley

    Cindy Russell, MD, Physicians for Safe Technology

    Annie J. Sasco, MD, DrPH, SM, MPH, retired Director of Research,INSERM (French NIH); one-time Unit Chief, IARC-WHO


    Public Comments: Organizations

    Association Alerte Phonegate (Dr. Marc Arazi)

    EMF Research Committee, Korean Institute of Electromagnetic Engineering in addition to Science (KIEES), South Korea

    Environmental Health Trust

    Environmental Working Group

    More Information

    Peer Review

    The members of the ii peer review committees for the NTP meeting have been announced.

    David Eaton, PhD, University of Washington, Chair

    Technical Panel 1: Reverberation Chamber Exposure System: Assess the reverberation sleeping room technology scientific discipline for evaluating the effects of prison theater Galvanic cell telephone radiofrequency radiations exposure inwards rats in addition to mice.

    Members:
    Frank Barnes, PhD, University of Colorado Boulder
    Asimini Kiourti, PhD, Ohio State University
    James Lin, PhD, University of Illinois at Chicago

    Technical Panel 2: NTP Findings inwards Rats in addition to Mice: (1) Review in addition to evaluate the scientific in addition to technical elements of the study in addition to its presentation; (2) Determine whether the study’s experimental design, conduct, in addition to findings back upwards the NTP’s conclusions regarding the carcinogenic activity in addition to toxicity of the examination agent.

    Members:
    Rick Adler, DVM, PhD, DACVP, Glaxo Smith Kline
    Lydia Andrews-Jones, DVM, PhD, DACVP, Allergan, Inc,
    J. Mark Cline, DVM, PhD, DACVP, Wake Forest School of Medicine
    George Corcoran, PhD, ATS, Wayne State University
    Susan Felter, PhD, Proctor & Gamble
    Jack Harkema, DVM, PhD, DACVP, Michigan State University
    Wolfgang Kaufmann, DVM, PhD, DECVP, Fellow IATP, Merck (retired)
    Tyler Malys, PhD, National Cancer Institute
    Kamala Pant, MS, BioReliance
    Matthias Rinke, DVM, PhD, FTA Pathology, CVP, Fellow IATP, Bayer Pharma (retired)
    Laurence Whiteley, DVM, PhD, DACVP, Pfizer 



    Jan 29, 2018 (Updated Jan 31, 2018)

    The next information was excerpted from the Federal Register.

    On Jan 29, 2018, the National Toxicology Program (NTP) announced a coming together to peer review ii draft NTP Technical Reports on Cell Phone Radiofrequency Radiation. These reports nowadays the results of NTP studies conducted to evaluate the impact of prison theater Galvanic cell telephone radiofrequency radiations exposure inwards mice in addition to rats.

    The peer-review coming together volition live held at the National Institute of Environmental Health Sciences (NIEHS) inwards Research Triangle Park, NC in addition to is opened upwards to the public. Registration is requested for attendance at the coming together either in-person or past times webcast in addition to to nowadays oral comments. Information most the coming together in addition to registration volition live available at https://ntp.niehs.nih.gov/​go/36051.

    Meeting

    Tentatively scheduled for March 26, 2018, 8:30 a.m. to adjournment on March 28, 2018, at to a greater extent than or less 5:00 p.m. Eastern Daylight Time. The preliminary agenda volition live available at https://ntp.niehs.nih.gov/​go/​36051 in addition to volition live updated 1 calendar week before the meeting.

    Document Availability

    The NTP volition post the ii draft technical reports at 12 noon (Eastern Standard Time) on Friday, Feb 2 on the NTP spider web site: https://ntp.niehs.nih.gov/​go/​36051.

    Deadlines

    Written Public Comment Submissions: March 12, 2018
    Registration for Oral Comments: March 12, 2018
    Registration to Attend Meeting In-person: March 28, 2018
    Registration to View Webcast: March 28, 2018

    Background

    Personal (cellular) telecommunication is a speedily evolving technology scientific discipline that uses radiofrequency release energy or radiations for mobile communication. According to a 2016 survey, 95 pct of American adults instantly purpose prison theater Galvanic cell phones. Given such broad use, adverse wellness effects shown to live associated with prison theater Galvanic cell telephone purpose could live a widespread world wellness concern.

    The U.S. Food in addition to Drug Administration (FDA) nominated prison theater Galvanic cell telephone radiofrequency radiations for NTP study because (a) widespread human exposure is possible, (b) electrical flow exposure guidelines are based largely on protection from astute injury due to thermal effects, (c) footling is known most the potential wellness effects of long-term exposure to radiofrequency radiation, in addition to (d) currently available human studies convey establish express evidence of an increased opportunity of cancer from prison theater Galvanic cell telephone use.

    NTP studied inwards rats in addition to mice the effects of exposure to prison theater Galvanic cell telephone radiofrequency radiations from ii scheme modulations: Global System for Mobile Communications in addition to Code Division Multiple Access. NTP released the “Report of Partial Findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation inwards Hsd: Sprague Dawley SD Rats (Whole Body Exposure)” inwards May 2016 (https://doi.org/​10.1101/​055699). The partial findings volition live included inwards the draft NTP technical study for rats. The ii draft NTP technical reports nowadays results for all NTP studies on rats in addition to mice on the toxicity in addition to carcinogenicity of prison theater Galvanic cell phone-emitted radiofrequency radiation.

    Public Comment Registration

    NTP invites written in addition to oral world comments on the draft NTP technical reports: Guidelines for Public Comments.

    The deadline for submission of written comments is March 12, 2018. Written world comments should live submitted through the coming together website. Persons submitting written comments should include name, affiliation, mailing address, phone, email, in addition to sponsoring organisation (if any). Written comments received inwards reply to this notice volition live posted on the NTP website, in addition to the submitter volition live identified past times name, affiliation, in addition to sponsoring organisation (if any). Comments that address scientific or technical issues volition live forwarded to the peer-review panel in addition to NTP staff prior to the meeting.

    Registration to render oral comments is on or before March 12, 2018, at https://ntp.niehs.nih.gov/​go/​36051. Registration is on a first-come, first-served basis, in addition to registrants volition live assigned a number inwards their confirmation email. Oral comments may live presented inwards soul at NIEHS or past times teleconference line. The access number for the teleconference trouble volition live provided to registrants past times e-mail prior to the meeting. Each organisation is allowed 1 fourth dimension slot per comment period. The agenda allows for ii world comment periods: The starting fourth dimension comment menstruation on the exposure scheme (12 commenters, upwards to v minutes per speaker), in addition to the 2nd comment menstruation on the NTP findings inwards rats in addition to mice (24 commenters, upwards to v minutes per speaker). After the maximum number of speakers per comment menstruation is exceeded, individuals registered to render oral comment volition live placed on a await listing in addition to notified should an opening operate available. Commenters volition live notified later March 12, 2018, the deadline to register for oral world comments, most the actual fourth dimension allotted per speaker.

    If possible, oral world commenters should ship a re-create of their slides and/or tilt or talking points to Canden Byrd past times email: NTP-Meetings@icf.com past times March 12, 2018.

    Background Information on NTP Peer-Review Panels

    NTP panels are technical, scientific advisory bodies to render independent scientific peer review. These panels assistance ensure transparent, unbiased, in addition to scientifically rigorous input to the program. Scientists interested inwards serving on an NTP panel should render their electrical flow curriculum vitae to Canden Byrd past times email: NTP-Meetings@icf.com.

    More information most the meeting

    http://bit.ly/FedRegNTP

    https://ntp.niehs.nih.gov/​go/​36051

    Information most NTP Partial Report of Findings

    http://bit.ly/NTPpartreport


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