Cure Alzheimer's Fund Makes Potential Game Changing Investment Inwards Alzheimer's Research
“We volition endure leading the agency inward an exciting novel expanse of study. The information from this first volition drive much faster evolution of therapies, both to forestall Alzheimer's affliction in addition to arrest its progress.” Jeff Morby
Baca Juga
The intellectual uppercase that comes from this query volition non endure hidden away inward the hopes of making billions of dollars.
Scientist worldwide volition select access to the scientific findings in addition to intellectual capital. Imagine, unleashing hundreds of scientist that powerfulness otherwise endure stymied or underutilized; in addition to then, allowing them to collaborate. There is a argue why they say - 2 heads are amend than one.
The full general in addition to administrative costs of the Cure Alzheimer's Fund are paid out of bag each twelvemonth past times the founding families of the CAF (the McCances, the Morbys in addition to the Rappaports).
When someone asks me where I mean value they should donate to Alzheimer's query my answer is ever the same -- Cure Alzheimer's Fund.
No donation is likewise small, or likewise big.
Please consider sharing this article in addition to the information below amongst family, relatives in addition to friends. Also, via social media on Google+, Facebook, Twitter in addition to on message boards.
There is Hope. Please consider a donation to the Cure Alzheimer's Fund.
| Subscribe to the |
Largest Single Private Investment inward Alzheimer’s Whole Genome Sequencing Targets Effective Therapies in addition to Cure
$5.4 Million Awarded for Research to Guide Alzheimer’s Drug Development
Understanding who is most susceptible to Alzheimer’s affliction in addition to developing early on detection models, effective therapies in addition to maybe a cure, is the destination of the largest unmarried mortal scientific grant ever invested inward Alzheimer’s Whole Genome Sequencing (WGS) focused on families afflicted amongst the disease.
Influenza A virus subtype H5N1 $5.4 meg contribution announced today from the non-profit Cure Alzheimer’s Fund to Massachusetts General Hospital (MGH) volition let state-of-the-art whole genome deoxyribonucleic acid sequencing to farther empathize the genetic roots of Alzheimer’s disease.
Over the final viii years the Cure Alzheimer’s Fund has teach i of the fundamental players inward identifying in addition to funding frontline query that is changing the confront of Alzheimer’s research. In 2008, the showtime stage of its Alzheimer's Genome Project (AGP) amongst MGH identified several novel Alzheimer’s genes in addition to was named a “Top Ten Medical Breakthrough” past times TIME magazine.
This report volition aim at discovering the genetic switches controlling the Alzheimer genes in addition to how they are triggered past times other genes in addition to past times environmental inputs. It volition examine deoxyribonucleic acid variants inward the Alzheimer genes that influence run a endangerment for the disease. While the showtime stage of the Alzheimer’s Genome Project create upwards one's withdraw heed “what” genes influence Alzheimer’s, the minute stage volition role Whole Genome Sequencing to create upwards one's withdraw heed “how” these genes confer increased run a endangerment for, or inward some case, protect against the disease.
Over the class of the side past times side 12-18 months, the report volition obtain the consummate genomic sequences of to a greater extent than than 1,500 subjects inward families that select Alzheimer’s, in addition to volition include over 100 encephalon samples. The genomes of household unit of measurement members amongst the affliction volition endure compared to those members who select been spared the affliction to position the sites inward the genome that influence run a endangerment for Alzheimer’s -- the first-ever whole genome sequencing projection targeting Alzheimer's affliction based on household unit of measurement samples.
The findings volition non endure proprietary in addition to volition endure made freely available to the scientific community worldwide therefore that the whole champaign tin brand role of the information to movement the scientific discipline forward. Currently, scientists select express agreement nigh the total genetic make-up of Alzheimer’s disease. Without to a greater extent than inward depth information, it is impossible to create upwards one's withdraw heed who is most at run a endangerment of the affliction or to regain a cure.
“We volition endure leading the agency inward an exciting novel expanse of report that is merely inward its infancy,” said Jeff Morby, chairman in addition to co-founder of CAF. “No i else inward this expanse of report volition endure on our timetable or select our sample size. It volition brand a huge contribution to the champaign in addition to hopefully convey us a pace closer to solving the mystery of Alzheimer’s.”
“This query is searching for genetic factors that influence run a endangerment for getting the affliction in addition to acquit on encephalon pathology,” said Professor Rudy Tanzi of MGH in addition to Harvard Medical School who volition atomic number 82 the project. “We are taking payoff of cutting border technology scientific discipline to regain how our genes create upwards one's withdraw heed susceptibility to Alzheimer’s affliction in addition to volition role this cognition to guide drug uncovering efforts.”
“This is an ambitious novel collaboration addressing a major wellness attention work facing our nation,” said Peter L. Slavin MD, president of MGH. “It expands our electrical flow operate amongst the Cure Alzheimer's Fund, which has dramatically advanced Alzheimer’s query amongst the identification of to a greater extent than than 120 novel candidate genes. We volition right away endure able to mine this information for novel levels of exceptional in addition to hand novel promise to patients hither in addition to around the world. “
“The application of comprehensive whole genome deoxyribonucleic acid sequencing to position the factor variants that influence run a endangerment for Alzheimer’s affliction is absolutely essential for agreement the biological underpinnings of this terrible disease,” said Tanzi.” This is unprecedented exam of the genome inward families afflicted amongst Alzheimer’s affliction in addition to nosotros await that these findings volition supply valuable novel clues nigh how to effectively process in addition to forestall Alzheimer’s disease.”The National Institute on Aging in addition to the National Human Genome Research Institute at NIH, are scaling upwards related large-scale genomics efforts inward Alzheimer’s affliction equally a real high priority Presidential initiative. According to Morby, at that spot should endure a position out of opportunities for synergy amongst the CAF/MGH project.
“The information from the WGS first volition drive much faster evolution of therapies, both to forestall the affliction in addition to arrest its progress,” said Morby. “This approach is highly efficient. While the dollar commitment is significant, the cost-per-discovery volition endure quite low.”
“We are non focused on incremental progress, but instead are going for the “long exceed downward field” for a meaning impact,” said Morby. “Our projects select established novel paradigms for agreement the real basic causes of Alzheimer’s.”
About CAF
Cure Alzheimer's Fund is a populace charity established to supply funding for targeted query into the causes of Alzheimer’s disease. Cure Alzheimer's Fund supports in addition to funds query amongst the highest probability of slowing, stopping or reversing Alzheimer's disease. For to a greater extent than information delight take in http://www.curealzfund.org/
About MGH
Massachusetts General Hospital, established inward 1811, is the master copy in addition to largest pedagogy infirmary of Harvard Medical School. The MGH conducts the largest hospital-based query computer programme inward the United States, amongst an annual query budget of to a greater extent than than $500 meg in addition to major query centers inward AIDS, cardiovascular research, cancer, computational in addition to integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, systems biology, transplantation biological scientific discipline in addition to photomedicine.
- Alzheimer's Disease Statistics
- Test Your Memory for Alzheimer's (5 Best Tests)
- What is the Difference Between Alzheimer’s in addition to Dementia
- Dementia in addition to the Eight Types of Dementia
- What is Alzheimer's Disease?
- Learning How to Communicate amongst Someone Suffering From Alzheimer's Disease
Original content Bob DeMarco, the
