How Much Does Bexarotene Cost, Volition Alzheimer's Patients Purchase It Off Label?

Do you lot know where I tin purchase Bexarotene? Do you lot know a MD that would prescribe Bexarotene off-label for my mother? Are you lot going to purchase Bexarotene for Dotty?

By +Bob DeMarco 
+

The Alzheimer's community caught on burn downward alongside the word that an already approved (FDA) cancer drug, Bexarotene, erased beta amyloid (Abeta) from the brains of mice stricken alongside Alzheimer's disease. It did this inwards a thing of hours in addition to days.

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Lets seat it this way. The phones of doctors, neurologists, in addition to pharmacists all over the basis were ringing off the wall on Fri alongside loved ones of Alzheimer's patients asking, tin I purchase Bexarotene (brand cite Targretin)?

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I received emails bespeak questions similar these:

• Do you lot know where I tin purchase Bexarotene?
• Do you lot know a MD that would prescribe Bexarotene off-label for my mother?
• Are you lot going to purchase Bexarotene for Dotty?

I answered those query equally follow: at most pharmacies including Walmart, No, I can't beak over Dotty's person wellness data without her permission.

Here is i query that no i did ask. How much does Targretin (Bexarotene) cost?

Targretin is a tier v drug, this agency it is real expensive. An Internet search indicated that 30, 75mg capsules terms $1,156.64.

If the drug were approved for my woman raise past times her healthcare provider it would terms $381.69 (this can't happen). Although it would shipping her right into the Medicare donut hole. She already takes i real expensive Alzheimer's drug, in addition to a few other medications.

Further enquiry indicated that most cancer patients have got to a greater extent than than i capsule a day. One thing nosotros don't know. If inwards fact Bexarotene proved effective for handling of Alzheimer's, what is the right daily dosage? 75 mg, 150mg, 225mg, more? How many capsules each day?

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Best I tin say virtually 2,000 cancer patients have got taken the drug. It appears that the drug is condom based on clinical testing, FDA approval, in addition to the available research. I am existence asked if I recall roughly Alzheimer's patients volition outset taking the drug. My reply is uncomplicated in addition to at nowadays forward, YES. I have got no uncertainty this volition happen.

All kinds of drugs are existence taken for uses other than that for which they are intended. Oxycodone is a adept representative in addition to you lot are welcome to search Google word to larn more. It is/was existence sold at epidemic levels right hither inwards Florida. Here is what Dr. Gary Landreth, Professor of Neurosciences, Alzheimer Research Laboratory Case Western Reserve University, School of Medicine, said,

"Don't endeavor this at domicile because nosotros don't know what dose to give, nosotros don't know how often to give it, in addition to at that topographic point are a few nuances to its administration. So i shouldn't move prescribing it off-label."

I know that many of you lot are likely thinking, why can't nosotros only enhance our hand, volunteer, in addition to acquire this drug tested right now? I tin assure you lot they would have got a M volunteers inwards virtually 8 minutes. Unfortunately, the drug is going to have got to acquire through several rounds of clinical testing earlier the drug is approved for Alzheimer's. This volition takes years.

Will the drug e'er acquire tested in addition to acquire approved past times the FDA for Alzheimer's? T

he electrical flow drug Targretin is scheduled to lose its patent inwards 2016. So, inwards club for Targretin to move financed into a Phase three clinical case it volition demand to move re-engineered in addition to re-patented to build the numbers work. In other words, it is unlikely that anyone is going to stride upwards in addition to finance the testing of a drug that is probable to move an available generic past times the fourth dimension it is approved for Alzheimer's patients. 

Here is a annotation to Dr. Gary Landreth in addition to his colleagues, acquire the drug through Phase 1 in addition to Phase ii clinical trials in addition to thus telephone telephone me. We volition have got upwards a collection in addition to finance the Phase three clinical trial. 

Yeah, I know most people recall that sounds nutty, nosotros are talking $50 meg dollars, perchance to a greater extent than inwards this solar daytime in addition to age. Estimated annual sales of Namenda are running over $1.2 billion annually right now.

So Alzheimer's patients are already spending the large bucks. Next upwards is a examination of 12 patients to encounter how Bexarotene is tolerated. We should have got those results past times the halt of the year.

Original content Bob DeMarco, the

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